The Topics

Every subject we publish on.

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  • 01Evidence reviews
  • 02Practical guidance
  • 03Protocol notes
All articles

Latest Articles

The complete archive, newest first — concepts, evidence reviews and practical guidance.

Simple prepared meal on a stone counter in daylight
Protein

Protein Intake: How Much Do You Actually Need?Preview content · not yet available

Grams per kilogram, the per-meal ceiling for muscle protein synthesis, and where the age adjustment comes from.

12 min readUpdated September 2026Reviewed by Dr. M. Aurelio, MD
Man in profile beside a limestone wall in late afternoon light

Enclomiphene raises endogenous testosterone by acting on the hypothalamic-pituitary axis rather than replacing hormone from outside the body. This is what the published literature says about its effect on sperm production.

9 min readUpdated 4 August 2026Reviewed by Dr. Adrian Vaux, MD
Blood collection tubes on a stone laboratory surface
Energy Balance

Metabolic Adaptation: What Actually Slows During A DeficitPreview content · not yet available

Reduced non-exercise activity, thyroid shifts and the size of the effect reported in controlled feeding studies.

10 min readUpdated August 2026Reviewed by Dr. M. Aurelio, MD
Man mid-set with a loaded barbell in a stone-walled gym
Strength

Protecting Lean Mass While Losing WeightPreview content · not yet available

A share of total weight lost is lean tissue. What resistance training and protein intake do to that ratio, and how it is measured.

10 min readUpdated August 2026Reviewed by Dr. M. Aurelio, MD
Morning light across a stone kitchen counter with a glass of water
Sleep Architecture

What Deep Sleep Is ForPreview content · not yet available

Slow-wave sleep, growth hormone pulsatility and memory consolidation — the measurable functions of the first half of the night.

10 min readUpdated August 2026Reviewed by Dr. M. Aurelio, MD
Physician reviewing laboratory results at a stone desk
Stress Load

Cortisol: What The Curve Actually DescribesPreview content · not yet available

Diurnal rhythm, the awakening response, and why a single random cortisol draw tells you close to nothing.

9 min readUpdated August 2026Reviewed by Dr. M. Aurelio, MD
Simple Roman meal on a travertine stone table
Food Quality

Ultra-Processed Food And Spontaneous OvereatingPreview content · not yet available

The controlled inpatient trial that reported a meaningful daily intake difference on matched macronutrients.

9 min readUpdated July 2026
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Programming

Minimum Effective Volume For Men Over FortyPreview content · not yet available

Weekly set counts, frequency, and where the returns flatten once recovery capacity rather than effort is the constraint.

11 min readUpdated July 2026
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Circadian Rhythm

Light Timing And The Clock You Cannot Argue WithPreview content · not yet available

Morning light exposure, evening suppression of melatonin, and the shift-work data that makes the mechanism hard to dismiss.

8 min readUpdated July 2026
Man and his partner walking a quiet stone street in late afternoon light
Alcohol

Two Drinks And Your Sleep ArchitecturePreview content · not yet available

Suppressed REM, a fragmented second half of the night, and the recovery cost measured the following day.

7 min readUpdated June 2026
Physician reviewing results at a stone desk
Conditioning

VO2 Max As A Mortality MarkerPreview content · not yet available

What the cohort data reports about cardiorespiratory fitness and all-cause risk, and how the measurement is actually taken.

9 min readUpdated June 2026Reviewed by Dr. M. Aurelio, MD
Laboratory vials on a travertine surface
Recovery

Sleep Restriction And TestosteronePreview content · not yet available

The controlled restriction studies, the size of the reported decline, and how quickly values recover on normal sleep.

7 min readUpdated June 2026Reviewed by Dr. M. Aurelio, MD
Man at the end of a training session in low morning light

Reading is the first step. Data is the second.

Laboratory results, health history and licensed clinician review determine whether any treatment discussed in these articles is appropriate — including whether treatment is indicated at all.

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Editorial & Medical Notice

Caesar publishes educational reference material. It is not a diagnosis, a prescription, or a promise of an individual result. Treatment decisions belong to you and a licensed physician who has reviewed your history and laboratory work. Our content is written by our editorial team, cited to primary literature, reviewed by a licensed clinician, and re-reviewed on a fixed schedule.